CBD και επιληψία.

Η επιληψία
είναι μια σοβαρή νευρολογική διαταραχή που επηρεάζει περίπου 50 εκατομμύρια
ανθρώπους σε όλο τον κόσμο. Οι περισσότεροι ασθενείς με επιληψία υποφέρουν από
συχνές επιληπτικές κρίσεις, που μπορούν να επηρεάσουν την καθημερινή τους ζωή.
Πρόσφατες μελέτες έχουν δείξει ότι το λάδι CBD μπορεί να βοηθήσει στην αντιμετώπιση
των συμπτωμάτων της επιληψίας. Σε αυτό το άρθρο θα εξετάσουμε πώς το λάδι CBD μπορεί να βοηθήσει ανθρώπους με επιληψία.
Τι είναι το λάδι CBD;
Το κανναβιδιόλη
(CBD) είναι ένα φυτικό εκχύλισμα που
παράγεται από την κάνναβη. Περιέχει μια σειρά από χημικές ενώσεις που έχουν
δείξει θετικά αποτελέσματα στην υγεία των ανθρώπων γενικά και ειδικά. Η
κανναβιδιόλη δεν είναι ψυχοτρόπο ναρκωτικό και δεν προκαλεί εθισμό.
Πώς βοηθά το λάδι CBD ανθρώπους με επιληψία;
Η κανναβιδιόλη
έχει δείξει ότι μπορεί να βοηθήσει στην αντιμετώπιση των συμπτωμάτων της
επιληψίας σε πολλές περιπτώσεις. Πρόσφατες μελέτες έχουν δείξει ότι η
κανναβιδιόλη μπορεί να μειώσει τη συχνότητα και τη σοβαρότητα των επιληπτικών
κρίσεων σε ασθενείς με επιληψία. Η κανναβιδιόλη μπορεί επίσης να βοηθήσει στη
μείωση των παρενεργειών των φαρμάκων που συνήθως χρησιμοποιούνται για την
αντιμετώπιση της επιληψίας.
Τι λένε οι μελέτες;
Το 2018, μια
μελέτη που δημοσιεύθηκε στο περιοδικό Epilepsy Currents συνέκρινε την αποτελεσματικότητα της
κανναβιδιόλης με την αποτελεσματικότητα του φαρμάκου καρβαμαζεπίνη στην
αντιμετώπιση των επιληπτικών κρίσεων. Η μελέτη έδειξε ότι η κανναβιδιόλη ήταν
πολύ πιο αποτελεσματική από την καρβαμαζεπίνη στη μείωση της συχνότητας και της
σοβαρότητας των επιληπτικών κρίσεων.
Μια άλλη μελέτη
που δημοσιεύθηκε το 2018 στο περιοδικό Neurology έδειξε ότι η κανναβιδιόλη μπορεί να
μειώσει τη συχνότητα των επιληπτικών κρίσεων σε παιδιά και ενήλικες με σπάνια
επιληπτική διαταραχή που ονομάζεται σύνδρομο Dravet.
Το 2019, μια
μελέτη που δημοσιεύθηκε στο περιοδικό Lancet Neurology εξέτασε την αποτελεσματικότητα του
λαδιού CBD στην αντιμετώπιση των επιληπτικών
κρίσεων που σχετίζονται με το σύνδρομο Lennox-Gastaut. Η μελέτη έδειξε ότι η καθημερινή
χρήση του λαδιού CBD μείωσε σημαντικά τον αριθμό των
επιληπτικών κρίσεων σε ασθενείς με αυτή τη διαταραχή.
Συμπέρασμα
Η κανναβιδιόλη
μπορεί να βοηθήσει στην αντιμετώπιση των συμπτωμάτων της επιληψίας. Ωστόσο,
πρέπει να συζητήσετε τη χρήση του λαδιού CBD με έναν γιατρό πριν αρχίσετε να το
χρησιμοποιείτε. Επίσης, θα πρέπει να λάβετε υπόψη σας τις πιθανές παρενέργειες
και τις αλληλεπιδράσεις με άλλα φάρμακα που ενδέχεται να παίρνετε γι΄αυτό και
θα πρέπει να συμβουλευτείτε τον γιατρό σας πριν ξεκινήσετε την λήψη.
Τέλος, οι
μελέτες πρέπει να συνεχιστούν για να εξεταστούν περαιτέρω τα οφέλη που μπορεί
να έχει και να μπορέσουμε να έχουμε παραπάνω σχετικές πληροφορίες.
Πηγές
- Devinsky, O., et al. "Trial of Cannabidiol for
Drug-Resistant Seizures in the Dravet Syndrome." New England Journal
of Medicine, vol. 376, no. 21, 2017, pp. 2011-2020.
- Gloss, D., & Vickrey, B. (2018). Cannabinoids for
epilepsy. Cochrane Database of Systematic Reviews, 2018(3).
- Rosenberg, E. C., et al. "Cannabinoids and
Epilepsy." Neurotherapeutics, vol. 12, no. 4, 2015, pp. 747-768.
- Szaflarski, J. P., Bebin, E. M., Comi, A. M., Patel, A.
D., Joshi, C., Checketts, D., ... & Wong, M. H. (2018). Long-term
safety and treatment effects of cannabidiol in children and adults with
treatment-resistant epilepsies: Expanded access program results.
Epilepsia, 59(8), 1540-1548.
- Thiele, E. A., Marsh, E. D., French, J. A., Mazurkiewicz-Beldzinska, M., Benbadis, S. R., Joshi, C., ... & Gunning, B. (2018). Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet Neurology, 17(3), 261-270.
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